Ben Foden, Mike Tindall, Mark Cueto, Olly Morgan all included, as is Tom Palmer who will be injured for the whole tournament.
Jordan Crane, Michael Lipman, Dan Hipkiss and James Simpson-Daniel miss out, as does Steffon Armitage.
What are your thoughts?
Forwards: Tim Payne (Wasps), Andrew Sheridan (Sale), Matt Stevens (Bath), Phil Vickery (Wasps), George Chuter (Leicester), Dylan Hartley (Northampton), Lee Mears (Bath), Steve Borthwick (Saracens), Nick Kennedy (London Irish), Tom Palmer (Wasps), Simon Shaw (Wasps), Tom Croft (Leicester), James Haskell (Wasps), Lewis Moody (Leicester), Tom Rees (Wasps), Nick Easter (Harlequins), Luke Narraway (Gloucester).
Backs: Delon Armitage (London Irish), Olly Morgan (Gloucester), Mathew Tait (Sale), Mark Cueto (Sale), Paul Sackey (Wasps), Ugo Monye (Harlequins), Jamie Noon (Newcastle), Mike Tindall (Gloucester), Riki Flutey (Wasps), Shane Geraghty (London Irish), Danny Cipriani (Wasps), Toby Flood (Leicester), Danny Care (Harlequins), Harry Ellis (Leicester), Ben Foden (Northampton).