Robin McBryde has made four changes (and one positional switch) to the side that snuck past Japan 22-18 in Osaka last weekend.
Cardiff Blues flanker Josh Navidi makes his debut in a side that also sees Tom Prydie, Rhys Gill and Andries Pretorius come into the starting team. The only change in the front row sees Saracens prop Gill come into the side alongside Emyr Phillips, who will win his second cap, and Blues prop Scott Andrews.
The new look back row sees James King switch to blindside, with Navidi coming in at openside flanker and Andries Pretorius starting for the first time for Wales at number eight. There is just one change behind the backline where Prydie comes onto the wing.
“We were proud of the side’s effort last weekend but know we will have to step it up again on Saturday,” said Head Coach for the Japan tour Robin McBryde.
“It was good to see the character of the squad come through in the first test and we will need that again.
“The players have again all put their hands up for selection making it a tough call for us and that shows their determination to get out on the field and represent their country.
“Japan showed what they are capable of last weekend and we know we will have to be at our best to get the second victory and finish the season on a high.”
Liam Williams (Scarlets), Harry Robinson (Blues), Owen Williams (Blues), Jonathan Spratt (Ospreys), Tom Prydie (Dragons), Dan Biggar (Ospreys), Lloyd Williams (Blues), Rhys Gill (Saracens), Emyr Phillips (Scarlets), Scott Andrews (Blues), Bradley Davies (CAPT) (Blues), Lou Reed (Blues), James King (Ospreys), Josh Navidi (Blues), Andries Pretorius (Blues).
Replacements: Scott Baldwin (Ospreys), Rhodri Jones (Scarlets), Craig Mitchell (Exeter Chiefs), Andrew Coombs (Dragons), Dan Baker (Ospreys), Tavis Knoyle (Scarlets), Rhys Patchell (Blues), Dafydd Howells (Ospreys).