Andy Robinson makes one change to the starting XV, bringing in Greig Laidlaw for the now retired Dan Parks. The uncapped Duncan Weir and Stuart Hogg are on the bench.
Scotland head coach Andy Robinson said: “Congratulations to Greig on his first start. He is a gifted footballer who is acclimatising very well to the differing demands of the stand-off position from having spent most of his career at scrum-half. Having lost last weekend, I believe the time is right to move on and look to develop our emerging talent at stand-off.
“I’ve always stressed the importance of the A team and the part that both Duncan Weir and Stuart Hogg played in the game at Netherdale last week is another reason for my continued excitement and belief in Scottish rugby.”
15. Rory Lamont, 14. Lee Jones, 13. Nick de Luca, 12. Sean Lamont, 11. Max Evans, 10. Greig Laidlaw, 9. Chris Cusiter, 1. Allan Jacobsen, 2. Ross Ford (c), 3. Geoff Cross, 4. Richie Gray, 5. Jim Hamilton, 6. Alasdair Strokosch, 7. Ross Rennie, 8. David Denton
16. Scott Lawson, 17. Ed Kalman, 18. Alastair Kellock, 19. John Barclay, 20. Mike Blair, 21. Duncan Weir, 22. Stuart Hogg