20-year old Adam Ashe makes his debut for Scotland this weekend as one of four changes made by coach Vern Cotter to the side to play South Africa this weekend.
The Glasgow back-rower wins his first cap as one of four changes to the team that beat Argentina. Henry Pyrgos comes in at scrum-half for Grayson Hart, Chris Fusaro comes onto the blindside while Tim Swinson enters the engine room in place of teammate Gray.
On the bench, Tyron Holmes, the 28 year old Glasgow loose forward, has the chance to make his debut if brought on, while Euan Murray can win his 60th cap.
Scotland: 15 Stuart Hogg, 14 Sean Maitland, 13 Nick De Luca, 12 Peter Horne, 11 Tommy Seymour, 10 Duncan Weir, 9 Henry Pyrgos, 8 Adam Ashe, 7 Chris Fusaro, 6 Rob Harley, 5 Grant Gilchrist (c), 4 Tim Swinson, 3 Geoff Cross, 2 Ross Ford, 1 Al Dickinson
Replacements: 16 Kevin Bryce, 17 Moray Low, 18 Euan Murray, 19 Jonny Gray, 20 Tyrone Holmes, 21 Grayson Hart, 22 Dougie Fife, 23 Peter Murchie
Date: Saturday 28th June
Venue: Nelson Mandela Bay Stadium, Port Elizabeth
Kick-off: 1700 local, 1600 BST
Referee: Glen Jackson (NZ)